A new era in cancer treatment has finally arrived as well. Authority of the U.S. Food And Drug, FDA, on 29 April 2010 passed a Provenge (sipuleucel-T) to use in the treatment of prostate cancer. Cell.jpg FDA Approval of this relief to many stakeholders, especially patients with prostate cancer in the U.S. is the second most cancer types after skin cancer (according to National Cancer Institute USA, in 2009 estimated 192 thousand new cases of prostate cancer registered in the U.S., 27 thousand of them died).
Provenge manufactured by Dendreon of Seattle's biotechnology factory established in 1992 by Dr. And Dr. Edgar Engleman. Samuel Strober (Stanford University professor)
Treatment with Provenge is different from cancer treatments that have been there (chemotherapy, surgery and radiotherapy). Provenge works by "educating" the immune system of patients (immune system). And just as important, the side effects of Provenge much lighter treatment of cancer with chemotherapy and radiation.
Cancer cells that had been freely proliferate around the prostate, will be bullied by the patient body's defense system that has been infused with provenge. Immune system of patients who received Provenge body will consider prostate cancer cells that have been entrenched in the body as foreign substances are dangerous and must be destroyed. Although cancer cells have spread everywhere (metastases), still considered an enemy by the immune system of patients.
Provenge treatment system such as this is considered as a milestone for the treatment of other cancers in the future. Some health practitioners in the United States considers the discovery of this drug as a phenomenal discovery. Dendreon Provenge producing factory mode is very different from usual pharmaceutical manufacturing. Provenge is not made en masse, but made a "taylor made" because raw materials are provenge immune cells (immune system) sufferer herself.
Briefly Provenge production method as follows: First blood to patients through a special machine to undergo leukapheresis process. In this process the patient immune cells is taken to be sent to the factory Dendreon. Immune cells are then exposed to a lot of type of protein found in all prostate cancer cells and added a few other substances to improve the immune system's ability to produce special Provenge for these patients. . Vaccine therapy is then inserted into the patient's body through the infusion to 3 times of usage. And the patients immune system will recognize cancer cells in the body as foreign objects or enemies to be destroyed next.
Seeing the results of clinical trials before these Provenge very significantly prolong patients with prostate cancer, many parties in the U.S. provenge predict will be a blockbuster drug - a drug that is very popular. Naturally Dendreon shares rose sharply recently. But not all cancer patients happy with this progress. It's known, treatment with provenge prices are still incredibly expensive. Estimated costs for three times infuse with Provenge will cost 93 thousand U.S. dollars, equivalent to 837 thousand million rupiah (able to buy three Toyota Innova)
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