Friday, July 2, 2010

The measurement of PCA3 in urine: prostate cancer screening



Learning about BPH, and one appeal from the BPH diagnosis was cancer of the prostate yes itself is actually from ya .. although i have ever read and I remember from konsulen surgical mentors I've ever finished it, prostate cancer if it actually would make a great ga appeal from the BPH diagnosis if prostate cancer because it usually ga symptoms. But ya if ya can be dilogikain aja gw mah's words, is not prostate cancer and BPH were equally enlarged and close the urethra (the urethra), we, can brarti aja difficult urination symptoms.

Now, if we want to diagnose BPH or prostate cancer was one of the supporting inspection by checking the protein level of PSA (Prostate specific Antigen) in the blood.

* Concentration;4 showed no abnormalities in the prostate gland.
* Levels 40-10 indicate no likelihood of prostate cancer or BPH. If found between PSA levels between 4-10 we usually count PSAd, namely PSA level divided by the size or volume of the prostate obtained from the ultrasound prostate (then = transrektal ultra sound). If the value PSA; 0.15 then the probability that prostate cancer is greater. Thus, if following a biopsy to confirm diagnosis of prostate cancer was. While if the level;0.15 then do not have to be done biopsy.
* Concentration; 10 then the likelihood of prostate cancer, and thus no value PSAd to decide what to do a biopsy or not.

In some people who checked the results and PSA levels high (10) but the results did not show results biopsy cancer, making doctors ask if the patient is not prostate cancer, or cancer cells are not affordable when done taking biopsy materials. Therefore the experts are looking for a more specific marker than PSA, for prostate cancer screening. Unlike the PSA which can be increased with benign prostate disease until the disease with high malignancy, PCA3 is specific to prostate cancer. In men who have elevated levels of PSA and previous negative prostate biopsy, determination of PCA3 appears to assess the prediction results re biopsy.

So can I pull the conclusion is, if we are suspicious of prostate cancer, then we do a PSA was high PSA results, but negative biopsy results then we should examine levels of PCA3. This examination to determine whether the decision should be re bipsi or not. But unfortunately not all medical facilities to provide this PCA3 examination.

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